This brochure, complementary to the document “PREVENTION AND EARLY DIAGNOSIS OF OTOTOXIC HEARING LOSS: CODEPEH 2020 recommendations“, deals with a scientific review of the early detection, prophylaxis, monitoring and treatment of ototoxicity in the paediatric population, which causes a deterioration in hearing ability with significant consequences. Ototoxic drugs represent one of the main causes of hearing loss that can be prevented and/or minimised. As in the case of any other type of deafness, its early detection and appropriate treatment can avoid the consequences associated with it.